Searchable abstracts of presentations at key conferences in endocrinology

ea0016p352 | Growth and development | ECE2008

Evaluation of insulin sensitivity in growth hormone (GH) deficient children before and at the end of rhGH therapy

Savastio Silvia , Bellone Simonetta , Bellone Jaele , Zanetta Fiorella , Di Dio Giuseppina , Giacoma Sara , Petri Antonella , Prodam Flavia , Corneli Ginevra , Bona Gianni , Aimaretti Gianluca

Introduction: Therapy with recombinant GH (rhGH) allows GH-deficient children (GHD) to reach an adequate adult stature. Previous studies have reported a significant rise in serum insulin levels during GH therapy. It has been demonstrated that insulin resistance is a risk factor for the development of DMT2, atherosclerosis, dyslipidemia and hypertension.Subjects and methods: Aim of our study was to evaluate changes in insulin sensitivity in a group of GHD...